For example, the antipsychotic Aripiprazole causes not only antagonism of dopamine D2 receptors in areas such as the mesolimbic area of the brain (which show increased dopamine activity in psychosis) but also agonism of dopamine receptors in areas of dopamine hypoactivity, such as the mesocortical area. In medicine, it can refer to a drug that can hold both antagonist (inhibitory) and agonist (excitatory) properties.Paul Davies has argued for the extension of the principle to cover the selection of our universe from a (postulated) multiverse: 'observers arise only in those universes where, like Goldilocks's porridge, things are by accident 'just right ''. Such a planet is colloquially called a 'Goldilocks Planet'. In simple words, it means that the user will have the best possible option, as the device is continuously trying to find one that suits most, with least difficulties. The Rare Earth Hypothesis uses the Goldilocks principle in the argument that a planet must be neither too far away from nor too close to a star and galactic center to support life, while either extreme would result in a planet incapable of supporting life. As Stephen Hawking put it, 'like Goldilocks, the development of intelligent life requires that planetary temperatures be 'just right ''. In astrobiology, the Goldilocks zone refers to the habitable zone around a star.

This effect was observed in infants, who are less likely to look away from a visual sequence when the current event is moderately probable, as measured by an idealized learning model. In cognitive science and developmental psychology, the Goldilocks effect or principle refers to an infant's preference to attend to events that are neither too simple nor too complex according to their current representation of the world.An animation used to study the Goldilocks effect in visual attention of infants

The goldilocks effect